LYFGENIA is an autologous hematopoietic stem cell-based gene therapy indicated for the treatment of patients 12 years of age or older with sickle cell disease and a history of vaso-occlusive events.2
VOE-CR = elimination of VOEs between 6 and 18 months post infusion.2
†VOEs were defined as any of the following events requiring evaluation at a medical facility: an episode of acute pain with no medically determined cause other than vaso-occlusion, lasting more than 2 hours, acute chest syndrome, acute hepatic sequestration, or acute splenic sequestration.2
‡After the primary evaluation period to last follow-up, 4 of 28 patients who achieved VOE-CR experienced VOEs.2
§The efficacy of LYFGENIA was studied in a single-arm, 24-month, open-label, multicenter Phase 1/2 study (Study 1-C) and a long-term follow-up study. In Study 1-C, 32 patients with a history of at least 4 VOEs in the 24 months prior to informed consent were evaluated for VOEs.2
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Support for you and your patients
Even before LYFGENIA is prescribed, your patients can enroll in and receive access to my bluebird support—a program that provides a range of support from helping to identify Qualified Treatment Center options for consultation to understanding insurance benefits and the process for prior authorization.
Patient Navigators are here to help with education, access, and logistics throughout the decision process and beyond.
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